A member asked:

What would cd8+/cd57+ large granular lymphocytes found in peripheral blood flow cytometry mean with loss of cd7 ?

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Dr. Thomas Knecht answered

Specializes in

Hi. Usually the purpose of flow cytometry is to determine whether an elevated white cell population (e.g., lymphocytes) is monoclonal and thus indicative of leukemia. Flow cytometry uses specific antibodies against specific cell surface white cell proteins (CD's, or Classification Determinants) to assess for monoclonalitiy of cell populations. What is report conclusion? Good luck!

Answered Sep 28, 2016

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