Is too lasix (furosemide) dangerous in nephrotic syndrome? can doses of 120 mg qd - bid to produce weight loss of 1-2 lbs./day result in further kidney damage?

Loop diuretics about: inhibiting tubular absorption, not glomerular filtration: the glomerular pathology of nephrotic syndrome. Thus no! If anything, Lasix, (furosemide) & other loop diuretics, up to a point, may be slightly protective by inhibiting concentration, diluting cleared proteins within the distal tubules & collecting ducts, etc. Nephrotic syndrome promotes edema due to loss of albumen: responsible for preventing edema.