A member asked:

I took one doxycycline 100mg pill, how long before this is out of my system, made me horribly nausted, reflux and leg cramps.

5 doctors weighed in across 3 answers
Dr. Dustin Colegrove answered

Specializes in Internal Medicine

It's a : Twice a day drug. You should feel better later today.

Answered 11/7/2014

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Will be gone soon: After only one dose, about half of the drug will be out of your system by 12 hours, and the drug levels will quickly diminish after that. Drinking lots of water may help. If your symptoms persist after more than a day or two you should see your doctor to consider other causes of your symptoms.

Answered 4/30/2015

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24-48 hours: It will take 24-48 hours to completely clear, but most is gone in 12 hours.

Answered 11/7/2014

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