A 35-year-old member asked:
what is edwards syndrome (trisomy 18)? what causes it?
2 doctor answers
Dr. Gregory Mosolf answered
24 years experience Pediatrics
Extra chromosome: In trisomy 18 the patient has an extra chromosome 18. This genetic disorder frequently causes heart and kidney defects. They may have a small head and jaw and usually have severe developmental delay. Here is a link http://www.Trisomy18.Org/site/pageserver?Pagename=whatist18_whatis.
Answered on Mar 31, 2016
Dr. James Ferguson answered
45 years experience Pediatrics
Non-disjunction: When cells divide to form an egg,the nl chromosomes (Chms) line up in pairs & one of each (23 pairs) goes to the egg .When the 18 Chms do not separate & 2 end up going to the egg, it will have 22 single Chms & a double 18 that combines with 23 single Chms brought by the sperm.Edwards syndrome represents 22 pairs & one triplet (18).The extra confuses the cells,resulting in malformations/disability.
Answered on Dec 11, 2019
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:
People also searched for:
Connect by text or video with a U.S. board-certified doctor now — wait time is less than 1 minute!