What does it mean when you have a low creatinine clearance?

Impairment: of kidney function. The kidneys are not filtering waste out of the blood as efficiently as they should. Most of the time low creatinine clearance is due to some sort of disease of the kidneys themselves like inflammation or decreased blood supply. Recurrent urinary tract infections can also damage the kidneys. Best to see a nephrologist for evaluation. Thanks for trusting HealthTap!