A member asked:

High rbc, rdw but low mcv mch mchc. b12 is also low at 300. sound like b12 induced anemia or something else? hdl chol also low (6pt) but rest perfect

4 doctors weighed in across 3 answers
Dr. Matt Wachsman answered

Specializes in Internal Medicine

Cannot say: Every lab I've ever seen puts 300 as totally normal. Every text says the cells should be big in megaloblastic anemia (hi MCV, etc). Low iron, small cells, low crit with iron deficiency.. most common type of anemia. without an exam, I can only give general information

Answered 11/3/2014

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Anemia: High RBC rules out the diagnosis of anemia, but how high decides the need for the treatment or not. B12 and hdl are low, both need to be treated.

Answered 11/3/2014

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Anemias: Low mcv,mch, and mchc can occur with iron deficiency but the rbc count would usually be low. Some hereditary anemias like Thalassemia may have higher rbc counts,though. B12 deficiency generally has a high MCV. A hematologist is best qualified to evaluate you and your findings.

Answered 11/3/2014

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