A member asked:

My doctor has me on 37.5 phentermine 2x a day. she gave me didrex 50mg 3x a day to start on the day i run out of phentermine. any issues with that?

5 doctors weighed in across 4 answers
Dr. Darrell Herrington answered

Specializes in Family Medicine

Not recommended : The cardiovascular risks outweigh any benefit of these medications.

Answered 11/2/2014

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Concern: Phentermine 37.5mg is the usual maximum daily dose. I am not clear why you need Didrex or why you will run out of phentermine. Combination of the 2 could lead to hypertensive crisis or tachy-arrythimia and will increase risk of complications. Avoid pregnancy while on phentermin

Answered 9/28/2016

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Dr. Ward Dean answered

Specializes in Holistic Medicine

Okay to switch: Phentermine and Didrex are in the same class--both are basically analogs of amphetamines. Some people respond to one drug better than another. The main disadvantage of Didrex is its cost.

Answered 9/28/2016

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Weight loss: That much Phentermine can and will affect your sleep cycle. Also, please stop the Phentermine 2 weeks before any surgery to avoid cardiac arrythmias and possible death.

Answered 9/28/2016

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