Benadryl (diphenhydramine).....: is probably the most readily available sedating antihistamine. It is a common ingredient in over-the-counter (OTC) preparations for sleep, such as Tylenol (acetaminophen) PM -- the PM part is diphenhydramine, the generic name for Benadryl. Another one I like to use is hydroxyzine (also known as Vistaril or Atarax) but that is only available as a prescription, however its metabolite is Zyrtec, which is OTC.
Answered 6/19/2016
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