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A 35-year-old member asked:

If i took one imodium (loperamide) plus an hour ago can i take promethazine?

1 doctor answer2 doctors weighed in
Dr. Ralph Morgan Lewis
Family Medicine 38 years experience
Best not to: Imodium (loperamide) & Promethazine have an additive effect such that you risk severe constipation/paralytic ileus. Give the Imodium (loperamide) time to work. Continue to replace fluids—water or beverage with electrolytes (sodium, potassium). If no improvement or if worse, see your doc for evaluation & treatment.

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Last updated Aug 10, 2017

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