Can you get brain damage from abusing dramamine (dimenhydrinate)?

Not necessarily: Dramamine (dimenhydrinate) should not be associated with brain damage. That being said, any drug used in an abusive fashion has the potential to be damaging to organs such as liver, kidneys, heart, or brain. It all depends on the drug and how the body activates it as well as eliminates it. Prudence is in limiting the amount of drug and frequency of use.

Not good: Its not good to abuse any drug including over the counter medications. Please follow the package inserts to avoid such problems.