A member asked:

My sis tested (+) factor v leiden and her dr suggested i get tested. i was fixing to start clomid (clomiphene) 4 secondary hypergonadism. r serms contraindicated?

A doctor has provided 1 answer
Dr. Rebecca Gliksman answered

Specializes in Internal Medicine

FH Leiden factor: Estrogens increase the risk of clotting. Clomid (clomiphene) is a non steroidal selective estrogen receptor modulator.It is not an estrogen. It has not been associated with significant increase in clotting to date, so should be OK. With FH of Leiden positive (I assume means deficient in Leiden V) which increases the risk of clots, get tested and let your doctor know of the results prior to starting.

Answered 9/12/2014

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