I have been taking 5-htp 100mg daily and 25mg pristiq (desvenlafaxine) for 4 weeks and starting to feel agitated, short of breath, tired .and a bit dizzy. ?

More needs to be: known about 5-HTP before recommending its use. There have been recent reports of eosinophilia myalgia syndrome associated with its use or contamination. You can read about this on Web-MD. Pristiq (desvenlafaxine) can also cause a similar set of side effects in a small minority of people.Also starting two serotonergic agents at the same time is not advised. (increased risk of serotonergic syndrome) Ask your doctor.

Why are you taking: 5-Hydroxytryptophan & Pristiq together? Does your psychiatrist have any idea that you are combining these? Is your psychiatrist aware of your symptoms. Combining these medications can ^ potential for serotonin syndrome. Serotonin Syndrome can cause nausea /vomiting /diarrhea, abdominal pain, stiffness or spasm of muscles,fever, shivering, ^ sweating, hallucinations, confusion, visual changes, ^