A member asked:

Can i take tylonol 3 and ibuprofen with melatonin? had wisdom tooth surgery two days ago

6 doctors weighed in across 2 answers

No problems: In recommended doses, this combination should pose no problems. However, both Tylenol (acetaminophen) #3 and melatonin are sedating, and taking both of them may be cumulative. Bypass the melatonin during this time if you are able to do so.

Answered 8/18/2016

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Dr. Michael Yap answered

Specializes in Nephrology and Dialysis

I would say no...: I see that you are already on lorazepam (Ativan) and Tylenol 3 may make you even more drowsy. I would also recommend not taking melatonin or "natural" meds. You can take ibuprofen and some regular acetaminophen as directed on the bottle, but I would not do this for more than a few days.

Answered 8/29/2014

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