A member asked:

How is it possible that sickle-cell disease are resistant to malaria, meaning they can't get malaria. how is this possible?

A doctor has provided 1 answer
Dr. James Ball answered

Specializes in Pediatric Hematology and Oncology

Unstable red cells: Malaria infects red blood cells. In order to propagate, malaria needs the red cells to survive being infected, so that the infection can persist, infecting other red blood cells. Sickle red cells are not stable at all, which does not allow the infection to last in those patients.

Answered 4/2/2017

3.8k views

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