A member asked:

Can you tell me the physiology of allergic rhinitis?

A doctor has provided 1 answer
Dr. Michael Rupp answered

Specializes in Allergy and Immunology

Not Simple: Answering this question in 400 words is a little difficult. Allergic rhinitis occurs because of histamine release triggered by mast cell degranulation resulting from IgE antibodies bound to allergens sticking to receptors on the mast cells. Once histamine is released then swelling, itching, sneezing, can occur. Later eosinophils migrate into the area and creates congestion.

Answered 11/15/2014

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