How safe is the parkinson tablet sinemet (carbidopa and levodopa)?

Ther are side effect: Sinemet (carbidopa and levodopa) average satisfaction score 62% of patients are at least somewhat satisfied with sinemet (carbidopa and levodopa). All medicines may cause side effects, but many people have no, or minor, side effects. Confusion; constipation; diarrhea; dizziness; drowsiness; dry mouth; headache; increased sweating; loss of appetite; nausea; taste changes; trouble sleeping; upset stomach; urinary tract infection; vomiting.

Very safe: This medicine has been out for forty years and has been a miracle drug for pd patients. There are potential issues for people who have been on it for a long time or at high doses (ie fluctuations, dyskinesias), but nearly every pd patient who goes on it feels better. It will not damage your liver, kidneys or any other organ. Because of the above issues, it may not be the first med used in pd.