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A 25-year-old female asked:

why does primary hypoaldosteronism lead to increased renin and angiotensin ii, but secondary hypoaldosteroninim does not?

1 doctor answer1 doctor weighed in
Dr. Chan Hwang
Physical Medicine and Rehabilitation 27 years experience
Renin-AT II-ALD axis: With primary (1°) hypoaldosteronism, feedback on the renin-angiotensin (AT) II-aldosterone (ALD) axis would cause the kidneys to increase renin and thereby AT II to try ^ adrenal ALD. In 2° hypoaldo, there is usually kidney damage (for example, due to diabetes) which decreases renin and hence AT II (which is produced in response to renin). This causes ALD (which depends on AT II) to v (hence 2°).

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United Kingdom
A 22-year-old male asked:

What test tells the level of angiotensin II in us?

1 doctor answer2 doctors weighed in
Dr. Stuart Hickerson
Family Medicine 32 years experience
Test: You can measure angiotensin two levels. I would talk to your cardiologist or renal specialist about the need to do this.

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Last updated Aug 18, 2014

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