A member asked:

Can cortisone medication relieve painful muscle spasms throughout your body?

2 doctors weighed in across 2 answers

No: cortisone has nothing to do with muscle spasms. cortisone is an antiinflammatory and can work being injected directly into a joint or taken orally

Answered 8/17/2014

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Dr. Lee Peter Bee answered

Specializes in Internal Medicine

Possibly: All corticosteroids have anti-inflammatory effects, affecting cyclooxygenase pathway, interfere with inflammatory cascade, reduce the release of inflammatory mediators, cytokines, TNFs involved in the inflammatory response. Muscle tone and spasm are mediated through intrafusal and extrafusal fibers with gamma motor neurons. Corticosteroid may reduce muscle spasm caused by inflammation.

Answered 8/17/2014

3.8k views

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Can a cortisone injection in your thigh create muscle spasms?

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