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A member asked:
What is the connection between iga and ibd (crohns, uc)?
4 doctors weighed in across 2 answers
IgA: Immunoglobulin A is produced by intestinal epithelium. IgA is intended to be secreted into bowel lumen. It can back diffuse into blood and deposit in kidneys, inciting inflammation there. Crohn s disease increases this potential..
Answered 4/18/2017
3.8k views
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Autoimmunity: There is IgA autoreactivity to epithelial cell lines. The body reacting to itself as foreign. Have a great day! http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1906379/
Answered 8/9/2014
3.8k views
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