Could edema neutralize or reverse my normal orthostatic hypotension?

A sign: Edema can be a sign that your "tank is full"-that your volume status is positive or in other words you are not deplete of fluid. That's important because in that situation there may not be much more to be gained by adding extra salt in your diet or hydrating more vigorously. If orthostasis still problematic, then you will likely need to turn to alternative therapies such as midodrine,etc.