A member asked:

Is cymbalta (duloxetine) work well with risperdal? for anxiety and depression?

3 doctors weighed in across 2 answers

Reasonable combo: Cymbalta (duloxetine) is a SNRI for depression, anxiety and pain and Risperdal is a med that helps with agitation, paranoia. A low dose of Risperdal added to antidepressants can boost the antidepressant effects esp as it helps anxiety/agitation. Additional side effects are possible but can be monitored by prescriber. All patients on these meds should be regularly monitored.

Answered 4/12/2017

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Dr. Alan Ali answered

Specializes in Psychiatry

Cymbalta/Risperdal: Cymbalta (duloxetine) works for Depression/Anxiety, Risperdal is added on to decrease agitation & stabilize moods.

Answered 5/13/2015

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