Hyponatremia risk: Trileptal is basically Tegretol with a hydroxyl side group that prevents conversion to "Tegretol 10-11 epoxide)". Lamictal is supposedly slightly better for preventing manic episodes. The problem with Lamictal is you have to titrate it slowly to minimize the risk of Stevens Johnson Syndrome. You can get to a therapeutic level of Trileptal in days rather than months for Lamictal (Less SJS risk)
Answered 8/18/2015
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