A member asked:

What could possibly be causing left arm and left leg skin temperature changes (goes from hot to cold). i have seen so many doctors and no one knows?

A doctor has provided 1 answer
Dr. Paul Grin answered

Specializes in Pain Management

See pain management: specialist. Some continuous neuropathic pains are also maintained by the sympathetic nervous system and are designated as sympathetically maintained pain (SMP). The mechanism of SMP is unclear and several hypotheses have been offered. The most accepted theory that when peripheral nerves are damaged, alpha 1 (and possibly alpha 2) receptors may be up-regulated on afferent (sensory) neurons.

Answered 5/30/2018

3.8k views

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