What does numbness and tingling in the lips mean?

Could mean-or ???: a lot of things....sometimes occurs just before, during, or after migraine headaches. It could be the result of putting something directly on the lips that interacts and causes irritation. It could be signaling the deficiency of certain vitamin supplements such as B12, folate, (folic acid) or B6 (pyridoxine). You should get a metabolic evaluation.