A member asked:
Could protein pump inhibitors cause gallbladder problem (no stones, but ck hida scan 25%)? might gallbladder condition improve if i stop taking ppi?
3 doctors weighed in across 2 answers
PPI: PPI's reduce the acid in your stomach. By reducing the acid in the stomach you reduce some of the digestive functions of protein breakdown and release of pancreatic enzymes. Changing these digestive functions can affect the gallbladder. However, this may not be the only thing contributing to the gall bladder dysfunction.
Answered 7/16/2014
3.9k views
It is possible: The success of proton pump inhibitor has led to widespread use. In my 15+ years of practice, I do not believe I have seen anything to convince me that PPIs cause or worsen gallbladder disease. Often, PPIs are used because a physician is trying to rule out peptic ulcer disease or gastritis as a cause of upper abdominal pain. See a surgeon about your gallbladder. It may need to be removed.
Answered 7/17/2014
3.9k views
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