I had a headache from 4 pm - 5 am. i didn't take anything. i took excedrin around 4 am but it didn't help. then i took maxalt (rizatriptan) mlt around 5 am and it helped. can you take excedrin and maxalt (rizatriptan) for migraine?

Yes: These are different medications with different modes of action and can be taken together or one shortly after the other if needed.

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Yes: Yes you can take them together. One drug on the market, treximet, is very similar to that combination.