A member asked:

My blood test hastoxic granulation present polycromasia 1= and poikilocytosis 1+?

2 doctors weighed in across 2 answers
Dr. John Michel answered

Specializes in Family Medicine

See your doctor: These are unusual white cell changes that need to be reviewed. It can be associated with some blood diseases as well as liver or spleen problems. Might also be associated with some infectious process. See your doctor, have the doc review this with you , and you may need to see a hematologist.

Answered 7/10/2014

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Reactive changes,,,: These are changes that reflect a reaction of the blood to some stress. The toxic granulation is seen in the white cells from inflammation, while the polychromasia indicates release of premature red cells into the bloodstream due to marrow stress. The poikilocytosis also results from effects on the red cells producing abnormal shapes. The multiple myeloma can help these changes. Good luck.

Answered 11/12/2017

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