Taking zoloft (sertraline) and advair, possible side effects?

Many possible: Both zoloft (sertraline) and advair have possible side-effects. However, it may be especially worth mentioning that the anti-asthma medication advair combines a beta-agonist and a steroid. Both of these may affect mood, especially the former, which can cause nervousness and a "hyper" feeling. If zoloft (sertraline) is being taken for anxiety, the advair may work against it somewhat. Ask your doc if you are concerned.