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A member asked:
Tumor size 8.7cm er pr negitive but ihc total score is 3 positive.what does it mean and what is the treatment?
2 doctors weighed in across 2 answers
Breast cancer?: where is the tumor? I assume this is breast cancer, correct? ER-/PR-/her2neu 3 + cancer. will need to get staging scan to evaluate if there is any spreading of cancer to other organs. if no metastatic disease- definitely will need to get chemotherapy PLUS herceptin (trastuzumab) ( her2neu inhibitor) - then surgery -then radiation therapy- then maintenance herceptin (trastuzumab). Please discuss further with oncologist .
Answered 6/25/2014
3.9k views
Her 2 neu pos ER PR-: The cancer is questions is not sensitive to hormonal therapy or ablation. I presume this is breast cancer. It stains strongly for Her 2 neu. This means it requires Herceptin (trastuzumab) based chemotherapy as big as it is. A common chemotherapy given in this situation is Carboplatin , Docetaxel and Herceptin (trastuzumab). one cycle every 21 days x for 6 cycles. This is before the definitive surgery, mastectomy.
Answered 6/27/2014
3.9k views
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