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A 21-year-old member asked:

do we know what causes endometrial cancer?

4 doctor answers13 doctors weighed in
Dr. Marianne DiNapoli
Dr. Marianne DiNapoli answered
Obstetrics and Gynecology 8 years experience
Estrogen +more: Endometrial cancer is the most common gynecologic cancer. Risk factors for developing endometrial cancer all include over-exposure to estrogen. This can occur with hormone replacement therapy after menopause, starting menstruation at an early age, going through menopause at a late age, never having children, and obesity.
Dr. Katherine Sutherland
Gynecology 43 years experience
Many factors: The risk of endometrial cancer is increased by obesity, diabetes, and persistently high estrogen levels, such as may occur with a condition like polycystic ovaries. Genetics also plays a role, especially with lynch syndrome which increases colon, endometrial, and ovarian cancers. Use of oral contraceptives or the Mirena (levonorgestrel) iud can decrease the risk of endometrial cancer.
Dr. John Kirk
Dr. John Kirk answered
Obstetrics and Gynecology 27 years experience
We do not know: While medical experts have not determined the cause of uterine cancer (endometrial cancer), it seems clear that an association with duration of estrogen exposure is the major risk factor. This puts women who are obese, had early puberty and no pregnancies, a history of unopposed estrogen (as in hormone replacement with only estrogen) and post breast cancer tamoxifen use at more risk.
Dr. Dennis Higginbotham
Obstetrics and Gynecology 30 years experience
Unopposed estrogen: The majority of endometrial cancers occur in post-menopausal women who are overweight. After menopause the endometrium will continue to grow if stimulated by estrogen (adipose produces estrogen), without ovulation no menstrual period occurs to shed that endometrium. The constantly stimulated endometrium can eventually become a cancer.

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Similar questions

A 21-year-old member asked:

How is endometrial cancer treated?

2 doctor answers3 doctors weighed in
Dr. Mitchell Kamrava
Radiation Oncology 16 years experience
Surgery first: Endometrial cancer is first treated with surgery. This surgery will give results that will help determine the final stage of your cancer. Based on this and other information from your pathology report radiation and or chemotherapy may be recommended following surgery.
A 21-year-old member asked:

What are the risk factors for endometrial cancer?

3 doctor answers6 doctors weighed in
Dr. David Finke
Obstetrics and Gynecology 15 years experience
Read below: Endometrial cancer presents as spotting/bleeding in between periods, heavy periods, and postmenopausal bleeding. Risk factors include: obesity, early age of menstruation, late age of menopause, never having carried a pregnancy (nulliparous women), ovarian disease that leads to an imbalance of estrogen and progesterone, tamoxifen use, and genetic predisposition.
A 21-year-old member asked:

What type and grade of endometrial cancer do I have?

2 doctor answers2 doctors weighed in
Dr. Vasu Brown
Integrative Medicine 34 years experience
Need details: Hi can u repost your question please.
A 43-year-old member asked:

What are the symptoms of a recurrent endometrial cancer?

3 doctor answers9 doctors weighed in
Dr. Mitchell Kamrava
Radiation Oncology 16 years experience
It depends: It really depends on the clinical scenario but often times one of the more common presenting symptoms of recurrent endometrial cancer is vaginal bleeding.
A 31-year-old member asked:

Is pomegranate or soy good for endometrial cancer?

2 doctor answers2 doctors weighed in
Dr. Mary Vanko
Obstetrics and Gynecology 34 years experience
CANCER NUTRITION: Neither affects the clinical course.

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Last updated Mar 12, 2020

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