A member asked:

Does periactin (cyproheptadine hydrochloride) make you gain weight? please, need some answers?

A doctor has provided 1 answer
Dr. Joram Seggev answered

Specializes in Internal Medicine - Allergy & Immunology

Yes, it can: Periactin (cyproheptadine hydrochloride) (cyproheptadine), is mainly used as an antihistamine, particularly for cold-induced urticaria (welts caused by cold objects). It also has effects on the brain, including sedation and increase in appetite, leading to weight gain.

Answered 7/13/2018

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