A member asked:

Keratinocyte growth factor for hair loss treatment?

2 doctors weighed in across 2 answers
Dr. Joseph Eastern answered

Specializes in Dermatology

Not yet anyway: Keratinocyte growth factor (kgf) is a protein present in the epithelialization phase of wound healing. It may be responsible for part of the healing process, and possibly hair regrowth as well, but there is no proven way to add it externally or stimulate its secretion internally. At least not yet. If anyone tells you they can do this, demand scientific proof.

Answered 6/25/2012

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Dr. Michael Fisher answered

Specializes in Dermatology

KGF and hair growth: Abstract keratinocyte growth factor-2 (kgf-2) is found in dermal papilla fibroblasts and its receptor, fibroblast growth factor receptor 2 (fgfr2), in the neighboring outer root sheath of keratinocytes. Administration of recombinant human kgf-2 (rhkgf-2) at 10 ng ml(-1) significantly stimulated human hair-follicle cell proliferation in organ culture (26-35%). Thus, rhkgf-2 is a promising therapeut.

Answered 6/24/2019

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