Yes: Most thyroid problems are caused by autoimmunity, where one's immune system misclassifies their own proteins as foreign, and makes antibodies against them. Autoimmunity can cause a variety of thyroid problems including hypothyroidism (low), hyperthyroidism(high), goiter(big thyroid), & nodules(lumps). Autoimmunity does run in families, but can cause different problems in different family members.
Answered 6/23/2014
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