How to treat onychomycosis?

Oral Antifungals: Oral antifungals like Lamisil (terbinafine) or itraconazole, Fluconazole or ketoconazole are the best to treat fungus in the nails. Topical products do not penetrate deeply enough into the nail to kill the fungus, so are generally ineffective. However, using topical anti fungal medications after the nail fungus is clear is wise so as to minimize the risk of reinfection of the nail.

Pulse therapy: To add to dr. Ebner's excellent answer, it's been shown recently that oral Lamisil (terbinafine) is much safer than we used to think. The fda recently dropped the liver function test requirement because of this. Also ask your doctor about pulse therapy Lamisil (terbinafine) where you only take 1 pill a day for 7 days every 3 months. The cure rate is the same as taking it every day for 3 months.

Many options: There are many treatments available. Topical and oral medications can be used but must be used as prescribed to have any success. Laser treatment is also available and can be effective. That being said, the older we are the more difficult it is to get rid of it. One must be very patient regardless of the treatment. Curing nail fungus is a slow process that takes months to even over a year.