Is there a link between anencephaly and genetics? are they hereditary?

Loose link : All of the neural tube defects from anencephaly down down the back to spina bifida are all loosely linked through numerous genes.Recurrence risk after a first affected child is minimal, quoted as 1.9%, but would encompass any of the related defects.Most are considered single chance events, and pre-pregnancy supplement of Folic Acid has reduced the frequency.