A member asked:

Can you tell me how replication initiates in adenovirus dna?

A doctor has provided 1 answer
Dr. John Leander Po answered

Specializes in Infectious Disease

It's complicated: To simplify: Being a linear double stranded DNA virus, a bunch of viral proteins are encoded early in its replicative cycle in order to: 1)create a primer at its 5' end, and 2) make a DNA polymerase that can replicate its genome starting from the primer.

Answered 7/14/2014

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