A member asked:

Can you tell me how the body maintain homeostasis with basal cell carcinoma?

2 doctors weighed in across 2 answers

Hyaluronic acid: J Eur Acad Dermatol Venereol. 2011 Jun;25(6):679-87. doi: 10.1111/j.1468-3083.2010.03851.x. Epub 2010 Sep 16. Nodular basal cell carcinoma is associated with increased hyaluronan homeostasis. Tzellos TG1, Kyrgidis A, Vahtsevanos K, Triaridis S, Printza A, Klagas I, Zvintzou E, Kritis A, Karakiulakis G, Papakonstantinou E.

Answered 7/7/2014

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Shed antigen: The status for most basal cell carcinomas are well defined, with the lesion remaining in the skin for long periods, first healing with scab that falls off and then rescabs. Such skin lesions do shed antigen into the skin where they are recognized by dendritic cells that help the immune system recognize and control growth. Efudex (fluorouracil) removes suppressor cells and lets effector cells control tumor.

Answered 7/7/2014

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