A member asked:

Currently on hydrocodone 5mg plus acetaminophen 325mg pills for pain after hand surgery. is it safe to take a benadryl (diphenhydramine) a day as well?

3 doctors weighed in across 2 answers
Dr. Paul Grin answered

Specializes in Pain Management

Use with caution: both drugs increase sedation and drowsiness. Use these medications exactly as instructed by your doctor. Take care.

Answered 5/25/2014

4k views

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Dr. Richard Makowiec answered

Specializes in Hand Surgery

Yes: It is okay to take both but they may increase your drowsiness and fatigue. Best to avoid driving or operating machinery and use with caution. Definitely follow your prescribing physician’s recommendations.

Answered 1/5/2019

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