Causes rarely known: We rarely find the cause for hives that last longer than 4 weeks. Individual hives last less than 24 hours and don't leave any scars are usually benign (not due to some bad disease), even if they are very itchy and make you miserable. Initial treatment is with high doses of antihistamines. If unsuccessful, there are protocols as to how to proceed. See a board-certified allergist/immunologist.
Answered 9/29/2016
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