What to do if i have hives due to immunologic problem?

Similar treatment: The mechanism of chronic hives can be due to a transient autoimmune response to a recent viral infection. These hives are still treated in a stepwise fashion, beginning with antihistamines (H1 and H2) as a first start. However, if your hives are resistant to therapy, and If is believed you have autoimmune urticaria, you might well respond to Xolair (anti-IgE), recently approved for hives.