A member asked:

Why etoposide administered before ifosfamide in chemotherapy ?

3 doctors weighed in across 2 answers

NO SPECIFIC REASON: Here are 3 possible reasons: 1) Most clinical trials use this sequence, although it has been given after in other studies as well 2) Etoposide is a shorter infusion 1-2 hours, Ifosfamide typically hours to 24 hrs, requiring monitoring of urine 3) Giving etoposide 1st also allows opportunity to give IV hydration prior to ifosfamide

Answered 6/29/2014

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? Does it matter?: I do not believe that it matters how you give them. Either order is followed in my practice.

Answered 11/26/2014

3.5k views

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