Can you tell me for some women, secretion of gnrh is inadequate, they're consider sterile and are treated drugs that mimic it?

GnRH secretion: Some women (and men) fail to secrete GnRH from the hypothalamus (part of the brain). Therefore, there is no signal to the pituitary to make reproductive hormones (FSH and LH). In Europe, Factrel is available via an automated pump. In the US, we give fertility pts FSH and hCG to cause ovulation. For those women not trying to conceive, estrogen and progesterone hormone replacement is given.