A member asked:

How do gene defects cause different forms of muscular dystrophy?

7 doctors weighed in across 2 answers
Dr. Joshua Batt answered

Specializes in Emergency Medicine

Coding: Like the order of letters in a word can spell and mean something different, so too can the order and type of genes cause a particular disease presentation. When someone has genes for muscular dystrophy, it depends on how strong those genes are and what they code for that determines what form of dystrophy they will have.

Answered 12/11/2014

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Dr. George Gantsoudes answered

Specializes in Pediatric Orthopedic Surgery

Long answer : We are limited to 400 characters, so i can't go into a lot of detail. Duchenne muscular dystrophy is caused by the failure of the body to make dystrophin. Beckers dystrophy has more dystrophin, but not nearly as much as normal. There are other genetic defects that i don't have enough room to go into further detail. Try www.Aaos.Org or another reputable site.

Answered 3/10/2013

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