Can medications cause peripheral nerve disorders?

Yes: There are some medications that are associated with peripheral neuropathy, especially some chemotherapy agents. Some of these can be at least partially counteracted by vitamin supplementation, but it varies from drug to drug.

Yes: Peripheral neuropathies can occur as adverse events secondary to a number of medicines. Several cancer chemotherapies can have this complication, and more common drugs such as Dilantin may do this also. In some cases, use of vitamins concurrently could blunt the side effects. (e.g., metformin, by adding vitamin b-12 to the med).