A 44-year-old member asked:
Disclaimer

what role does the immune system play with ms?

3 doctor answers
Dr. Virginia Simnad
27 years experience Neurology
Pivotal role: This is a complex and not fully understood aspect of ms. Certain immune cell population recognize proteins in the insulation coating surround nerve fibers in the central nervous system as "foreign". This results in a cascade of events leading to injury of the insulation material and underlying nerve fiber. Other factors possibly separate from immune attack also play a role in ms.
Answered on Jun 24, 2015
5
5 thanks
Dr. Jack Mutnick
16 years experience Allergy and Immunology
Autoimmune disease: Ms is an autoimmune disease, so the antibodies in your system are working adversely against the neurologic system in your body. Much of the treatment is aimed at down-regulating this aberrant immune reaction.
Answered on Jan 8, 2013
1
1 thank
Dr. Bennett Machanic
51 years experience Neurology
Very complicated: Latest info suggests an inborn genetic susceptibility with environmental triggering events. The basic pathology causes the immune system to mistake brain and spinal cord myelin as a foreign entity. Data regarding grey matter involvement is starting to explain much of what is occurring. All current meds target lymphocyte trafficking, (t cells), but the b cell research is exciting.
Answered on Feb 20, 2013
3
3 thanks

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
Unlimited visits
$10/month

Related questions:

A 21-year-old member asked:
Dr. Virginia Simnad
27 years experience Neurology
Unclear: Lots of interest currently in the interplay of genetic background of a population and environmental triggers. No one clear winner here, but studies o ... Read More
1
1 comment
3
3 thanks
A 21-year-old member asked:
Dr. Leonard Spishakoff
Specializes in Addiction Medicine
No: Ms is thought to be caused by viral onfection ms can cause mood disorders etc which can be exacerbated by traumatic events.
5
5 thanks
A 29-year-old male asked:
Dr. Rishi Kumar
7 years experience Anesthesiology
Read on : Nerves are affected too early axonal degeneration is well known in ms the antibody is specific even in examples given, in ms the antibody is against o ... Read More
2
2 thanks
A 22-year-old member asked:
Dr. Virginia Simnad
27 years experience Neurology
Uncertain: Much interest recently in epstein barr virus (ebv), the virus causing mononucleosis and its association with future risk of developing ms. Other viru ... Read More
5
5 thanks

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
Unlimited visits
$10/month