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A 21-year-old member asked:

Is multiple sclerosis hereditary?

3 doctor answers6 doctors weighed in
Dr. J. patrick Tokarz
Specializes in Family Medicine
Worse: Many patients with MS fell worse in the heat.
Dr. Addagada Rao
General Surgery 56 years experience
No proof: No conclusive proof that m s is transmitted by genetics ( hereditary) but slightly higher incidence is noted in some families.
Dr. Bennett Machanic
Neurology 52 years experience
Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest.

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A 23-year-old member asked:

Is multiple sclerosis a hereditary condition?

3 doctor answers4 doctors weighed in
Dr. Virginia Simnad
Neurology 28 years experience
In part: Hereditary risk is one factor, but the interplay between genetic background and environment is likely in this disease. Identical twins studies show about a 30% risk for MS if one twin has the disease (certainly not 100%). Population studies show certain ancestry may increase or decrease risk (e.g. Northern european ancestry high, whereas asian, african, aboriginal very low).
CA
A 25-year-old member asked:

Does multiple sclerosis have a hereditary component?

3 doctor answers4 doctors weighed in
Dr. Virginia Simnad
Neurology 28 years experience
Yes: No single gene for MS has been found or likely to be found. Multiple genes have been identified which in different population studies worldwide seem to increase risk or protect against ms. The vast majority of these genes relate to immune system function. Genetic background, combined with environmental trigger likely trigger this disorder.

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Last updated Jun 3, 2016
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