A member asked:

My daughter has been diagnosed with ? mosaicism of the skin ? segmental vitiligo , how do we differentiate it ?

A doctor has provided 1 answer
Dr. Johanna Fricke answered

Specializes in Pediatrics - Developmental and Behavioral

Mosaicism in a girl : Means she developed from a single fertilized egg but has 2 or > sets of genes from either crossover during mitosis, mutation of a gene or chromosome or inactivation of an x chr. Clinical genetic evaluation , chromosomal microarray ; skin biopsy help diagnose. Hyper- or hypo- pigmented areas are usually streaks that follow lines of blashko, invisible in most of us, but can be whorls/swirls.

Answered 4/5/2016

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