Allergy: It's possible that the serum in the original bite contained material that caused additional allergic reactions in the surrounding skin. Have you applied cortisone type cream to the rash? Taking an antihistamine like benadryl(may cause drowsiness) will also help the reaction and the itch. If redness and burning appear you may be developing cellulitis which requires antibiotic medication and cream.
Answered 2/2/2019
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