A member asked:

1 why does seroquel (quetiapine) cause food craving? 2 to what extent? 3 what is the solution for weight gain and increased appetite while on seroquel (quetiapine)?

3 doctors weighed in across 2 answers

Antihisatmine: Seroquel or quetiapine exerts its main effects via the blockage of Dopamine receptors. A common side effect is weight gain and food craving which occurs secondarily to the blockage of histamine receptors. Unfortunately, little can be done to combat the weight gain aside from dietary modification. There are alternative antidepressants that cause less weight gain. Ask your doctor about these.

Answered 6/25/2014

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Dr. Milton Alvis, jr answered

Specializes in Preventive Medicine

No one fully knows: Study http://en.Wikipedia.Org/wiki/quetiapine ; look up the molecule on google images. As with all molecules, the molecule is simple; the fantastic complexity ; all responses are within the individual ingesting specific doses. This is the whole point of clinical trials, study the fda approved pis: http://www1.Astrazeneca-us.Com/pi/seroquel.Pdf ; http://www1.Astrazeneca-us.Com/pi/seroquelxr.Pdf.

Answered 4/14/2014

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