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A 48-year-old member asked:

i was just wondering why does malaria cause haemoglobinuria?

1 doctor answer3 doctors weighed in
Dr. Robert Isaacs
Family Medicine 39 years experience
Malaria: The malaria parasite infects red blood cells (rbc's) where it goes through several multiplication stages. The rbc eventually ruptures, releasing the parasites and haemoglobin. The haemoglobin is filtered by the kidney and is excreted into the urine. Each new parasite then goes on to infect another rbc and the cycle is repeated.
Dr. Robert Isaacs
Family Medicine 39 years experience
Provided original answer
The haemoglobin can discolour the urine, even to the point of turning it quite dark. 100+ years ago this was called the blackwater fever.
Apr 25, 2014

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A 51-year-old member asked:

Why does malaria cause hemoglobinuria?

1 doctor answer1 doctor weighed in
Dr. Heidi Fowler
Psychiatry 25 years experience
Hemoglobinuria: "Haemoglobinuria is one of the manifestations of severe malaria and results from severe intravascular haemolysis. Glucose-6-phosphate dehydrogenase (G6PD) deficiency has been implicated in its aetiology. Haemoglobinuria may be associated with severe anaemia and, less frequently, acute renal failure." See: http://www.malariajournal.com/content/11/1/336

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Last updated Apr 25, 2014

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